While it will rely on the skills of established researchers in population genetics, biological anthropology and the history of epidemics, this axis also intends to open up to the skills of the "Corps, normes, santé" team in health law, ethics and odontology. Knowledge will gain in comprehensiveness through an exploration of the epidemic body in its multiple facets.
Projects
The horizon of understanding the epidemic phenomenon will also be broadened by taking into account data from soils understood as environmental reservoirs of pathogens and their vectors. The team wants to be a pioneer in this type of approach, which is still on the fringe of scientific approaches, whereas soils are undeniably important epidemic foci because of their preservation of bacterial traces for many years.
This project is led by Maria De Grandis (PhD, CR EFS), Sylvie Fernandes (PhD, DR EFS) and Stéphanie Morin (PhD, CR EFS), with the technical support of Alexandra Grimaldi (Research Assistant EFS), Cécile Durousseau (Research Assistant EFS) and Thomas Granier (Research Assistant EFS)
In this project we are interested in red blood cell diseases and the vascular abnormalities in which they may be involved, with a particular focus on dyserythropoiesis and blood cell interactions in the circulation. Initially we will concentrate our efforts on sickle cell disease as a pathological model, then we will extend our methodology to explore other diseases, notably membrane diseases, in which potential defects in erythropoiesis have never been examined.
Our transfusion research is focused on improving transfusion products, with RBC as the primary focus.